San Antonio Spurs vs Chicago Bulls Prediction - 11/10/2025
Updated November 10, 2025
Updated November 10, 2025
The matchup between the San Antonio Spurs (7–2) and the Chicago Bulls (6–3) on Monday night might be the best game in the NBA on the night. The Bulls arrive into this game with an unbeaten record at home this season. But the Spurs are red-hot and will try to put a stop to Chicago's hot home start. Before tip-off from United Center, continue reading to get my Spurs vs Bulls prediction.
Pick: Bulls +3.5
Confidence: ★★★★☆
The Spurs arrive with strong form early in the season. They’re 7–2 and riding high after a 126‑119 victory over the New Orleans Pelicans in which De'Aaron Fox tallied 24 points shortly after returning from injury. Despite a hamstring issue earlier in the season, he appears sharp.
The Bulls are 6–3 and host this contest with their perfect 5‑0 home record on the line. But their injury list is troubling. Guard Coby White is out, forward/center Zach Collins is sidelined, and guard Josh Giddey is questionable with an ankle injury. They could really use Giddey on the floor if they want to win this game.
The play of Victor Wembanyama early in the season is a major storyline for the Spurs. Wemby is averaging 24.3 points and 12.9 rebounds per game. He does not appear to be impacted by being shut down last season due to deep vein thrombosis and appears to be as close to a lock as you can get in sports to win Defensive Player of the Year if he stays healthy this season.
Player | Prop |
|---|---|
De’Aaron Fox (Spurs) | Under 20.5 points |
Stephon Castle (Spurs) | Over 6.5 assists |
Josh Giddey (Bulls) | Over 8.5 assists (if he plays) |
Score Projection: San Antonio Spurs 114 – Chicago Bulls 115
Win Probability: Spurs 50%, Bulls 50%
Both of these teams are undefeated at home so far this season. But the Spurs are just 2-2 on the road and have looked much less unbeatable than they look at Frost Bank Center. I'm going to take the points with the Bulls here, as I make this game close to a toss-up at United Center, while the Spurs would have the advantage if they were at home.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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