The Detroit Lions and Los Angeles Rams square off on Sunday afternoon in a huge Week 15 NFL game. Los Angeles enters as the favorite as they try to stay at the top of the NFC West. But Detroit’s high-octane offense and resilient identity have kept it in every game this season. Before this game with huge NFC playoff implications begins, you will find my Lions vs Rams prediction below.
Our Lions vs Rams Pick
Game Snapshot
- Matchup: Detroit Lions vs Los Angeles Rams
- Date & Time: Sunday, December 14, 2025, 4:25 p.m. Eastern
- Venue: SoFi Stadium, Inglewood, CA
- Broadcast: FOX
Key Storylines
Sunday’s showdown between the Lions and Rams is a big game for more than just playoff purposes. Longtime NFL fans will fixate on the quarterbacks, as former Rams starter Jared Goff now leads Detroit against his old club, while Matthew Stafford gets another chance to carve up a depleted Lions secondary that has lost key safeties Kerby Joseph and Brian Branch to injury.
The Rams are fighting to stay atop the NFC West and bolster their postseason seeding, while Detroit is clawing to stay within reach of the NFC North and secure a Wild Card berth. The status of Rams wide receiver Davante Adams is questionable, but the offense’s momentum remains strong thanks to Stafford’s MVP-caliber season and a versatile receiving corps.
Quarterback Play
Stafford has been one of the most productive signal callers in the league in 2025, ranking near the top in passing touchdowns and yardage. His connection with the duo of Nacua and Adams, especially in the red zone, makes the Rams’ passing attack lethal even without perfect health at all positions. Stafford’s ability to spread the ball around and generate big plays has been a significant factor in Los Angeles’s offensive success.
Goff continues to lead a potent Lions offense that ranks among the league’s highest scoring units. Detroit has thrived offensively behind Goff’s precise passing and a group of weapons that includes Amon-Ra St. Brown and Jahmyr Gibbs. Goff’s consistency and low interception totals have been key to Detroit’s success, though facing a stout Rams defense this week presents a much tougher challenge than usual.
Betting Trends & H2H
- The Rams are 9-4 against the spread so far this season.
- Detroit is 7-6 against the spread entering this contest from Inglewood.
- Detroit has gone over the total in 8 of their first 13 games.
- The under has hit in 7 of the Rams’ first 13 games.
Lions vs Rams Model Projection
Final Thoughts
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