Cincinnati Bengals vs Buffalo Bills Prediction - 12/7/2025
Updated December 4, 2025
Updated December 4, 2025
The Cincinnati Bengals head to Orchard Park on Sunday to face the Buffalo Bills in what could be the most entertaining game of Week 14 in the AFC. With both teams fighting to stay relevant in the playoff picture, both teams will need to find a way to get defensive stops against explosive offenses. Here, I break down the keys to this game and give you my Bengals vs Bills prediction for Sunday afternoon.
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Spread | Moneyline | Total |
|---|---|---|
Bills –5.5 | Bills –270, Bengals +220 | 53.5 |
On Buffalo’s side, Josh Allen has both arm strength and mobility. Against a pass defense that has been among the worst in the league, he is more than capable of making big plays. Buffalo is likely to be aggressive in keeping the ball in Allen's hands to try and create separation in this contest.
Cincinnati will start Joe Burrow, who recently returned from a turf‑toe injury. Burrow barely completed half of his passes against the Ravens last week. But he had two touchdown passes and didn't throw any interceptions. If he continues to get more comfortable on the field, the Bengals could get another big road win this week.
Score Projection: Cincinnati Bengals 27 – Buffalo Bills 31
Win Probability: Bengals 33%, Bills 67%
I'm taking the over in this matchup between the Bengals and Bills. Buffalo should win the game, but I'm expecting a back-and-forth affair where both offenses shine, especially if Burrow is able to play again for Cincinnati.
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