Buffalo Bills vs Pittsburgh Steelers Prediction - 11/30/2025
Updated November 29, 2025
Updated November 29, 2025
The Sunday afternoon clash between the Buffalo Bills and Pittsburgh Steelers is one of the biggest games of the week for the NFL's playoff picture. The Bills enter Week 13 holding the final AFC Wild Card spot, while the Steelers are trying to keep sole possession of the AFC North lead with a win. Before this huge matchup kicks off from Pittsburgh, continue reading to get my Bills vs Steelers prediction.
Pick: Steelers +3
Confidence: ★★★★☆
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Spread | Moneyline | Total |
|---|---|---|
Bills –3 | Bills –175 / Steelers +150 | 45.5 |
Buffalo’s Josh Allen must manage the pocket carefully. Without his starting tackles, he may face heavy pressure, reducing his ability to make downfield plays. Allen's scrambling ability will be more valuable than ever if Watt is able to get penetration on a regular basis.
Rodgers returns with full clearance for Pittsburgh this week. He has 19 touchdown passes and 7 interceptions on the season. Rodgers has thrown 5 touchdowns to DK Metcalf and that connection will be incredibly valuable for the Steelers here.
Score Projection: Buffalo 24 – Pittsburgh 27
Win Probability: Buffalo 50% / Pittsburgh 50%
Both of these teams are incredibly tough and this game will be a fight to the very end. But I think that Pittsburgh has a slight advantage heading into this contest. The Steelers' pass rush is among the best in football and we saw the Bills struggle to block against the Texans just over a week ago. I'll take the Steelers as a home dog, as they should pressure Josh Allen for most of the day at Acrisure Stadium.
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