San Antonio Spurs vs Memphis Grizzlies Preview & Prediction – 1/6/2026

The San Antonio Spurs will visit the Memphis Grizzlies on Tuesday night, with each team hoping to gain ground in the Western Conference standings. San Antonio sits near the top, while Memphis has struggled and is fighting to stay in the play-in conversation. Here, I break down this matchup between these Western Conference rivals and bring you my Spurs vs Grizzlies prediction for tonight.

Our Spurs vs Grizzlies Pick

Game Snapshot

• Matchup: San Antonio Spurs @ Memphis Grizzlies
• Date & Time: Tuesday, January 6, 2026, 8:00 PM ET
• Venue: FedExForum, Memphis, TN
• Broadcast: NBA League Pass

Key Storylines

San Antonio enters this game with a strong 25-10 record and has won its last four road games heading into this trip to Memphis. Their offensive balance and defensive discipline have kept them competitive, even while dealing with injuries to key contributors.

Victor Wembanyama, who averages 24.3 points and 11.7 rebounds per game, is listed as questionable after returning to practice following a left knee bone bruise suffered recently. His status will be a major factor for the Spurs’ ceiling in this matchup. Devin Vassell remains out with a groin issue, pushing additional responsibility onto players like De’Aaron Fox and Julian Champagnie, who has emerged as a reliable scorer off the bench. San Antonio’s trend of slow starts has been a talking point for coaches, with the team looking to improve its early level of energy in Memphis.

Memphis has struggled with injuries across its roster, affecting rotation depth and consistency. Ja Morant is questionable, and several rotation players like Vince Williams Jr., Cedric Coward, Ty Jerome, John Konchar, Scotty Pippen Jr., Brandon Clarke, and Zach Edey are either out or in uncertain condition. Jaren Jackson Jr. has been the Grizzlies’ most consistent performer, averaging 18.4 points per game, while Santi Aldama contributes on both ends of the floor. Memphis enters this game with four straight losses and will be eager to defend home court against one of the West’s stronger teams.

Head-to-Head & Betting Trends

• The Spurs have won both prior meetings this season against Memphis, including a 126-119 victory earlier this year.
• San Antonio is 18-16-2 against the spread on the season.
• The Grizzlies are 15-20 against the spread entering this matchup.
• The under is 21-14 in Grizzlies games this season.
• The under has gone 19-17 for the Spurs this year.

Best Player Props to Watch

Spurs vs Grizzlies Model Projection

Final Thoughts

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.