The Nevada Wolf Pack will travel to Laramie on Saturday to take on the Wyoming Cowboys in a Mountain West matchup between two struggling teams. Both teams are in the bottom four in the Mountain West standings this season, but someone has to win this matchup nonetheless. Before this game kicks off from Wyoming, continue reading to get my Wyoming vs Nevada prediction for Saturday afternoon.
Our Wyoming vs Nevada Pick
- Pick: Under 39.5
- Confidence: 4/5
Get more college football picks before Saturday’s action!
Game Snapshot
- Matchup: Wyoming Cowboys vs Nevada Wolf Pack
- Date & Time: Saturday, November 22, 2025, 2:00 PM ET (12:00 MT)
- Venue: War Memorial Stadium, Laramie, Wyoming
- Broadcast: Mountain West Network
Key Storylines
Wyoming is coming off a rough offensive showing in a 24–3 loss to Fresno State. Their offense has struggled to be consistent and there are growing calls to shake things up under center. Nevada is riding high after a dominant 55–10 win over San Jose State, their first win in Mountain West Conference play this season. Nevada will try to build on that performance against a Wyoming team that is struggling mightily to put points on the board.
Wyoming is celebrating Senior Day this weekend. Former University of Wyoming great and current NFL star Josh Allen will be honored. The excitement surrounding that could give Wyoming a lift, though it might not help the Cowboys on offense unless Allen were to suit up and play quarterback for them.
Quarterback Play
Kaden Anderson remains the starter for Wyoming. He has thrown for 1,791 yards this season, but his 11 touchdowns and 10 interceptions highlight how inconsistent he’s been. His production has dipped in recent weeks and the coaching staff is reportedly considering rotating in freshman quarterback Mason Drube to breathe life into the offense.
Nevada’s offense is spearheaded by Carter Jones, who completed 16-of-19 passes for 195 yards, two touchdowns, and no interceptions in his last outing. That kind of efficient, mistake-free performance is exactly what Nevada needs to stay competitive in Laramie.
Betting Trends & H2H
- Wyoming is 5–5–0 against the spread this season.
- Nevada is 4–5–1 against the spread this year.
- Wyoming games have stayed under their totals 8 times in 10 games.
- Nevada has also stayed under the total in the majority of their games. They have seen 6 of their 10 games stay under their totals.
- The Cowboys have won four of the last five meetings against the Wolf Pack.
Wyoming vs Nevada Model Projection
- Score Projection: Wyoming 21 – Nevada 14
- Win Probability: Wyoming 72%, Nevada 28%
Final Thoughts
I’m not all that confident in backing either team to win this game on Saturday. But I am more confident in the game staying under the total in Laramie. Wyoming has been a frequent under team throughout the season. That should continue in this game, as their offensive struggles and their respectable defense should add up to another low-scoring game featuring the Cowboys.
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