The Creighton Bluejays and Gonzaga Bulldogs will do battle on Tuesday night in Spokane. Gonzaga enters 2‑0 and has looked sharp thus far, while Creighton is a 1‑0 team aiming to make a statement on the road. Gonzaga is a heavy favorite going into this matchup, where size could end up being the deciding factor. Before tip-off, you can find my Creighton vs Gonzaga prediction below.
Our Creighton vs Gonzaga Pick
Pick: Creighton +10.5
Confidence: ★★★☆☆
Game Snapshot
- Matchup: Creighton Bluejays @ Gonzaga Bulldogs
- Date & Time: Tuesday, November 11, 2025, 10:00 PM ET
- Venue: McCarthey Athletic Center, Spokane, Washington
- Broadcast: ESPN
Key Storylines
- Gonzaga has opened the season 2‑0 and arguably looks more polished. They beat Oklahoma by 15 points in their last game and they will try to get another win over a team from one of the premier college basketball conference in the country here.
- Creighton arrives with a record of 1‑0. Their first win was a blowout win over South Dakota. This game will serve as a much bigger test for both of these teams given their recent histories of success in college basketball.
- Size could be the determining factor in this game. The Bluejays no longer have Ryan Kalkbrenner to patrol the painted area. That could mean a huge night for Graham Ike, who is more experienced and more physical than most of the bigs in college basketball right now.
- Both of these teams are ranked in the top 25 going into this contest. The winner of this game will shoot up the rankings, while the loser could find themselves out of the rankings early in the year. There is plenty of season left for both of these teams, but the stakes in this matchup are higher than those in most non-conference games in November.
Head‑to‑Head & Betting Trends
- Gonzaga is 2-0 against the spread going into this matchup.
- Creighton failed to cover the spread in its first game of the season.
- Gonzaga has stayed under the total in each of their first two games.
- The Bluejays stayed under the total in their season opener as well.
- Gonzaga is ranked eighth in the current KenPom ratings.
- Creighton is 45th in the current KenPom rankings.
Creighton vs Gonzaga Model Projection
Score Projection: Gonzaga 83 – Creighton 77
Win Probability: Gonzaga 88%, Creighton 12%
Final Thoughts
I am expecting Gonzaga to win at home to stay unbeaten early in the season. As for the point spread, I think that Creighton will cover the number as an underdog on the road. The Bluejays are much better than the Oklahoma team that Gonzaga tore through in their last outing. The Zags should win this game but it should be a respectable, single-digit margin when all is said and done.
Jay Sanin
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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