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Video: Tennessee vs Iowa State Prediction, Odds, & ATS Picks (March 27)

Tennessee vs Iowa State Prediction (March Madness 2026 - Sweet 16)

In this video, we break down Tennessee vs Iowa State in the NCAA Tournament Sweet 16:

  • The defensive philosophies that will feature in this game
  • A huge return for Iowa State entering the Sweet 16
  • Our best bet against the spread for this huge game in college basketball

Iowa State enters as a 4.5-point favorite going into the Sweet 16, as Rick Barnes looks to prove the doubters wrong in this game.