Los Angeles Rams vs Jacksonville Jaguars Prediction - 10/19/2025
Updated October 14, 2025
Updated October 14, 2025
The Los Angeles Rams and Jacksonville Jaguars will meet in London on Sunday at the iconic Wembley Stadium. Both of these teams are 4-2 on the season so far and a win here would be huge for the playoff hopes of whoever gets it. Before the action begins from England, continue reading to get my Rams vs Jaguars prediction.
Spread | Moneyline | Total |
|---|---|---|
Rams –3 | Rams –150, Jaguars +130 | 44.5 |
Matthew Stafford has been very good, throwing for 1,684 yards, 12 touchdowns, and just two interceptions. With Nacua’s injury, he may be more reliant on Davante Adams and secondary receivers stepping up. Trevor Lawrence’s success hinges on not turning the ball over. He has five interceptions already this year. If the Rams can bring pressure and force hurried throws, Lawrence may struggle to deliver consistently.
Score Projection: Rams 24 – Jaguars 23
Win Probability: Rams 52%, Jaguars 48%
This is going to be a tight game and the fact that it is being played in London should only make things less predictable than usual. The Rams' top target through the air being compromised from a health standpoint could end up being a major problem for them. I will take the Jags to cover the spread as an underdog, as they have won three of their last four games and could win what is close to a toss-up as far as I'm concerned.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
Affiliate Disclosure
ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
