Dallas Cowboys vs Carolina Panthers Prediction - 10/12/2025
Updated October 6, 2025
Updated October 6, 2025
The Dallas Cowboys will visit the Carolina Panthers in Week 6 of the 2025 NFL season on Sunday. The Cowboys enter this game at 2-2-1 following a blowout win over the New York Jets. They will take on a Panthers team that is 2-3 and looking to stay perfect on their home field for the season. Here, I take a closer look at this matchup and bring you my Cowboys vs Panthers prediction for Week 6.
Betting Line | Odds |
|---|---|
Spread | Cowboys -3.5 |
Moneyline | Cowboys -185 / Panthers +155 |
Total | Over/Under 49.5 |
Dak Prescott has been a steady presence for the Cowboys, demonstrating efficiency through the air. Despite the absence of key receivers, Prescott ranks second in the league in passing yards and is tied for third with 10 touchdown passes.
Bryce Young has shown potential but remains inconsistent. He made key plays down the stretch to help his team defeat the Miami Dolphins at home in Week 5. But he will need to put up points more consistently over four quarters if he is going to lead his team to another win at home.
I don't feel all that strongly about betting a side in this game. This is the second straight road game for the Cowboys, while the Panthers were very fortunate to engineer a comeback win over the struggling Dolphins in Week 5. Instead, I'll take the over in this contest, as both of these teams have struggled to find their footing on defense.
