Milwaukee Bucks vs Memphis Grizzlies Preview & Betting Picks – 12/26/2025

The Milwaukee Bucks will travel to Memphis on Friday to take on the Memphis Grizzlies in a game between two of the most disappointing teams in the NBA this season. Both teams enter this contest having lost two of their last three games, but are coming off wins in their most recent outing. Which team will get its second win in a row? You will find my answer to that question below, as I make my Bucks vs Grizzlies prediction for tonight.

Our Bucks vs Grizzlies Pick

Game Snapshot

• Matchup: Milwaukee Bucks @ Memphis Grizzlies
• Date & Time: December 26, 2025, 8:00 PM ET
• Venue: FedExForum, Memphis, Tennessee
• Broadcast: NBA League Pass

Key Storylines

Injuries continue to play a large role in this game for both teams. The Bucks will be without Giannis Antetokounmpo due to a calf strain and Taurean Prince with a neck issue, while Gary Trent Jr. is listed as a game-time decision. Antetokounmpo’s absence dramatically affects Milwaukee’s scoring and defensive presence at the rim, reducing their ceiling and forcing others to step up. Ryan Rollins and Kevin Porter Jr. have assumed larger offensive roles in recent games, with Rollins leading the team in scoring.

Multiple rotation players are sidelined for Memphis, including Brandon Clarke, Scotty Pippen Jr., Ty Jerome, and Zach Edey. Ja Morant and Cedric Coward are both listed as questionable for this contest, meaning their status could shift pre-game as well. Memphis’ offensive rhythm has not been disrupted quite as dramatically as Milwaukee’s of late, but it’s hard to expect much consistency out of either of these banged-up teams.

Head-to-Head & Betting Trends

• This is the first of two regular-season meetings between the Bucks and Grizzlies this year.
• Both of these teams are 14-16 against the spread going into this matchup.
• The Grizzlies have stayed under the total in 19 of their first 30 games this year.
• The under is 18-12 in games involving the Bucks this season.

Best Player Props to Watch

Bucks vs Grizzlies Model Projection

Final Thoughts

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.