The Memphis Grizzlies visit the Minnesota Timberwolves on Wednesday night in one of two games on the NBA schedule. Both teams are coming off wins in their most recent games and will try to continue climing the Western Conference standings with a win in Minneapolis. Before tip-off, continue reading for my Grizzlies vs Timberwolves prediction in pro basketball.
Our Grizzlies vs Timberwolves Pick
Game Snapshot
- Matchup: Memphis Grizzlies @ Minnesota Timberwolves
- Date & Time: December 17, 2025, 8:00 PM ET
- Venue: Target Center, Minneapolis, Minnesota
- Broadcast: NBA TV
Key Storylines
Minnesota enters this contest as a solid home favorite thanks to a 17-9 record and a 9-4 record on their home floor. The Timberwolves have won two games in a row, including a 127-120 triumph over the Golden State Warriors while missing star Anthony Edwards. Edwards, the team’s leading scorer, is listed as questionable with right foot issues and his status will be critical for bettors to monitor right up until tipoff. Veteran Mike Conley is out with Achilles tendinopathy.
The Grizzlies come in with a 12-14 record but have won three of their last four games. They just rolled over the Los Angeles Clippers 121-103, led by Jaren Jackson Jr.’s 31 points and a breakout performance from sharpshooter Cam Spencer. Spencer scorched the nets with 27 points and seven three-pointers. Memphis continues to struggle with injuries and roster limitations, as big man Zach Edey is out for at least four weeks with an ankle issue and guard John Konchar recently underwent thumb surgery. Ja Morant is listed as questionable with an ankle injury, while several role players are out for this contest like Ty Jerome and Scotty Pippen Jr.
Head-to-Head & Betting Trends
- This is the first of four head-to-head matchups between the Grizzlies and Timberwolves this season.
- Minnesota is 10-16 against the spread this season.
- Memphis is 12-14 against the spread going into this matchup.
- The Timberwolves are 13-13 on over/unders going into Wednesday night.
- The Grizzlies have stayed under the total in 17 of their 26 games. They are tied for the highest percentage of unders in the NBA this year at 65.4% of their games.
Best Player Props to Watch
| Player | Prop |
|---|---|
| Anthony Edwards | |
| Rudy Gobert | |
| Jaren Jackson Jr. |

