Cleveland Cavaliers vs San Antonio Spurs Best Bet & Predictions - 12/29/2025
Updated December 29, 2025
Updated December 29, 2025
The Cleveland Cavaliers will take on the San Antonio Spurs on Monday night in an inter-conference matchup in the NBA. The Spurs have been one of the NBA’s top teams this season, yet they will be tasked with bouncing back from a shocking loss in their last outing here. Cleveland’s dynamic duo of Donovan Mitchell and Darius Garland is on the floor together again and will try to upset the Spurs in San Antonio. Before tip-off from Texas, you will find my Cavaliers vs Spurs prediction below.
Pick: | Spurs -2.5 |
Confidence: | 3/5 |
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Player | Prop to Watch |
|---|---|
Donovan Mitchell | Over 27.5 Points |
Victor Wembanyama | Over 10.5 Rebounds |
De’Aaron Fox | Over 5.5 Assists |
Score Projection: Cleveland Cavaliers 119 – San Antonio Spurs 125
Win Probability: Cavaliers 42%, Spurs 58%
I am going to lay the points with the Spurs at home in this matchup in the NBA on Monday night. The Spurs were shocked by the Jazz at home in their last game and that should light a fire under them going into a much bigger test. The Cavs will drop their third straight road game against a quality opponent in this matchup.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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