Cleveland Guardians vs Seattle Mariners: 2022 MLB Preview, Results & Betting Analysis

Updated October 28, 2026


Updated October 28, 2026

The Cleveland Guardians and Seattle Mariners met seven times during the 2022 MLB regular season, with both clubs competing for American League playoff positions.
Cleveland relied on strong pitching, contact hitting, and an aggressive approach on the bases. Seattle brought more power to the lineup and strengthened its rotation with the addition of Luis Castillo.
Their head-to-head games showed how differently those approaches could play out. Several contests were decided by one or two runs, while Seattle's pitching staff delivered two shutouts.
The Mariners ultimately won six of the seven meetings, including a three-game sweep at Progressive Field in September.
This historical matchup review examines both teams, their pitching strengths, the complete season series, and the betting lessons from their 2022 meetings.
Category | Cleveland Guardians | Seattle Mariners |
|---|---|---|
Division | AL Central | AL West |
2022 final record | 92-70 | 90-72 |
Division finish | 1st | 2nd |
Runs scored | 698 | 690 |
Runs allowed | 634 | 623 |
Run differential | +64 | +67 |
Manager | Terry Francona | Scott Servais |
Postseason qualification | Division winner | Wild Card |
Head-to-head wins | 1 | 6 |
Both teams reached the postseason in 2022.
Cleveland won the AL Central with 92 victories, while Seattle finished with 90 wins and secured an American League Wild Card berth.
Despite their similar records, the Mariners controlled the regular-season series.
Seattle's pitching was particularly effective, holding Cleveland to three runs or fewer in six of the seven games.
The teams played four games at T-Mobile Park in August and three at Progressive Field in September.
Date | Venue | Final score | Winner |
|---|---|---|---|
August 25, 2022 | T-Mobile Park | Mariners 3, Guardians 1 | Seattle |
August 26, 2022 | T-Mobile Park | Mariners 3, Guardians 2 (11 innings) | Seattle |
August 27, 2022 | T-Mobile Park | Guardians 4, Mariners 3 | Cleveland |
August 28, 2022 | T-Mobile Park | Mariners 4, Guardians 0 | Seattle |
September 2, 2022 | Progressive Field | Mariners 6, Guardians 1 | Seattle |
September 3, 2022 | Progressive Field | Mariners 4, Guardians 0 | Seattle |
September 4, 2022 | Progressive Field | Mariners 6, Guardians 3 (11 innings) | Seattle |
Season series: Seattle Mariners 6-1
The Mariners scored 29 runs across the seven games, compared with Cleveland's 11.
Seattle also won both extra-inning meetings.
The Guardians' only victory came on August 27, when they scored three runs in the eighth inning to overcome a late deficit.
Cleveland's success in 2022 was built around pitching, defense, and a lineup capable of putting the ball in play.
The Guardians were less dependent on home runs than many of their American League rivals.
Instead, they used contact hitting, speed, and situational offense to manufacture runs.
That approach helped Cleveland finish first in the AL Central despite entering the season with relatively modest expectations.
José Ramírez remained the most dangerous hitter in Cleveland's lineup.
The switch-hitting third baseman provided power, extra-base hits, and run production while anchoring an otherwise contact-oriented offense.
Andrés Giménez emerged as another important contributor.
His ability to hit for average, reach base, and play excellent defense gave the Guardians considerable value in the middle infield.
Steven Kwan also established himself as a reliable leadoff hitter during his rookie season.
Kwan's plate discipline and contact skills helped Cleveland create scoring opportunities without relying heavily on home runs.
Josh Naylor supplied additional power, particularly against right-handed pitching.
Together, these hitters gave the Guardians a balanced lineup.
However, Cleveland's offense could struggle when opposing pitchers limited singles and prevented runners from advancing.
That became a recurring problem against Seattle.
The Guardians had several dependable starting pitchers in 2022.
Shane Bieber led the rotation with his command, breaking pitches, and ability to work deep into games.
Triston McKenzie emerged as another effective starter, using his fastball and breaking pitches to miss bats.
Cal Quantrill provided consistency, while Zach Plesac and Aaron Civale also contributed starts throughout the season.
Cleveland's pitching staff was especially important because the offense was not built around overwhelming opponents with power.
The Guardians frequently needed their starters to keep games close and give the lineup opportunities to manufacture runs late.
Emmanuel Clase was one of the most effective relief pitchers in baseball during the 2022 season.
His high-velocity cutter made him difficult to square up, and his ability to protect narrow leads was a major advantage for Cleveland.
The Guardians were particularly dangerous when leading late.
Their combination of contact hitting, aggressive baserunning, and strong relief pitching made them well suited to close games.
Against Seattle, however, Cleveland often struggled to establish a lead before reaching the late innings.
Seattle entered the 2022 season hoping to end a postseason drought that stretched back to 2001.
The Mariners eventually accomplished that goal, finishing 90-72 and reaching the playoffs for the first time in 21 years.
Their success came through a combination of improved starting pitching, a strong bullpen, and timely power hitting.
The acquisition of Luis Castillo at the trade deadline further strengthened an already competitive pitching staff.
Julio Rodríguez quickly became one of Seattle's most important players.
The rookie outfielder provided power, speed, and defensive ability while establishing himself near the top of the lineup.
His offensive production gave the Mariners another dangerous hitter alongside veterans such as Ty France and Eugenio Suárez.
Rodríguez's ability to drive the ball and create scoring opportunities was particularly valuable in close games.
He would go on to win the 2022 American League Rookie of the Year award.
Cal Raleigh became an increasingly important part of Seattle's offense during the season.
The switch-hitting catcher provided power and played a major role in managing the pitching staff.
His ability to hit home runs gave the Mariners a different offensive dimension than Cleveland.
Raleigh was particularly influential during the September series at Progressive Field, hitting two home runs in Seattle's 6-1 victory on September 2.
Seattle acquired Luis Castillo from Cincinnati before the trade deadline.
The move gave the Mariners an established frontline starter for the final months of the season.
Castillo joined a rotation that already included Robbie Ray, Logan Gilbert, and George Kirby.
That depth allowed Seattle to compete against strong opponents without relying on one starting pitcher.
Castillo's impact was particularly apparent in the matchups with Cleveland.
He struck out 10 Guardians in a strong August 27 start, although Seattle eventually lost that game after its bullpen surrendered a late lead.
On September 2, Castillo returned to face Cleveland and delivered six scoreless innings in a 6-1 victory.
Both clubs had strong starting rotations, but Seattle's depth became a major advantage during their head-to-head meetings.
Castillo, Ray, and Kirby gave the Mariners several pitchers capable of limiting contact and working deep into games.
Cleveland's lineup was effective at putting the ball in play, but Seattle consistently prevented those opportunities from developing into substantial scoring rallies.
The Guardians were held scoreless twice during the seven-game series.
The two offenses approached scoring differently.
Cleveland relied on singles, baserunning, and situational hitting.
Seattle had more power throughout its lineup, with Rodríguez, Raleigh, and Suárez capable of changing a game with one swing.
That difference mattered in close contests.
A home run could provide Seattle with an immediate advantage, while Cleveland often needed several productive plate appearances to generate the same number of runs.
The Mariners' power was particularly effective in their September sweep.
Both teams possessed strong late-inning relief options.
Clase was a major advantage for Cleveland, while Seattle relied on several effective relievers, including Andrés Muñoz and Paul Sewald.
The August 27 meeting demonstrated that even a strong bullpen could have a difficult outing.
Seattle led 3-1 entering the eighth inning, but Cleveland scored three runs against Muñoz to take a 4-3 lead.
Clase then secured the save.
That result was Cleveland's only victory in the season series.
Seattle won three of four meetings at T-Mobile Park.
The Mariners then swept Cleveland in three games at Progressive Field.
The results demonstrated that Seattle's advantage was not limited to playing at home.
Its pitching staff performed effectively in both ballparks, while Cleveland struggled to generate consistent offense.
The first four games took place at T-Mobile Park.
Seattle won the opener 3-1 on August 25, limiting Cleveland to one run.
The following night, the Mariners earned a 3-2 victory in 11 innings.
That result gave Seattle a two-game lead in the season series.
Cleveland finally broke through in the third game.
The Mariners led 3-1 after seven innings, with Luis Castillo having delivered another strong start.
Castillo allowed one run and struck out 10 batters.
Seattle appeared positioned for another victory, but Cleveland rallied in the eighth inning.
The Guardians scored three runs against Andrés Muñoz to take a 4-3 lead.
Emmanuel Clase closed the game, earning his 30th save of the season.
The result was particularly unusual because Seattle's only three hits were home runs.
Rodríguez, Suárez, and Jake Lamb each went deep, but the Mariners could not generate enough additional offense.
Seattle responded immediately in the series finale.
The Mariners defeated Cleveland 4-0 behind a strong pitching performance from Robbie Ray.
The Guardians managed just five hits and failed to score.
Seattle finished the four-game home series with three victories.
The result also reinforced the importance of the Mariners' starting rotation.
The teams met again at Progressive Field for a three-game series in early September.
Seattle entered the series playing well, while Cleveland was attempting to maintain its position in the AL Central race.
The Mariners controlled all three games.
Seattle opened the series with a convincing 6-1 victory.
Luis Castillo delivered six scoreless innings, allowing Cleveland little opportunity to establish an offensive rhythm.
Cal Raleigh hit two home runs, providing the power Seattle needed.
The Mariners scored three runs in the sixth inning to extend their advantage.
Cleveland finished with nine hits but managed only one run.
The result highlighted a recurring issue for the Guardians: putting runners on base did not consistently translate into scoring against Seattle.
The Mariners followed with a 4-0 victory.
Robbie Ray earned the win as Seattle's pitching staff held Cleveland scoreless for the second time in the season series.
The Guardians struggled to produce meaningful scoring opportunities.
Seattle's victory secured the series win and extended its advantage in the head-to-head matchup.
The final meeting was the most dramatic game of the September series.
The contest was interrupted by a rain delay lasting more than four hours.
Cleveland managed to keep the game close, and the teams eventually reached extra innings tied at 3-3.
Seattle broke through in the 11th inning.
J.P. Crawford delivered the go-ahead hit before Cal Raleigh added a two-run home run.
The Mariners won 6-3, completing the sweep.
The victory was Seattle's seventh consecutive win overall and capped an undefeated road trip.
Because the original ATS.io article could not be recovered, its betting markets remain unknown.
There is no verified historical moneyline, run line, or Over/Under associated with this specific URL.
The results nevertheless provide useful insight into how the teams matched up during 2022.
Seattle won six of the seven meetings.
That represents an 85.7% head-to-head winning percentage.
However, that figure describes the completed season series. It should not be interpreted as a pregame win probability or evidence that every Seattle moneyline offered good value.
Evaluating an individual wager would require the odds available before that game.
A favorite can win and still have been overpriced, while an underdog can lose despite offering reasonable value.
Without the original prices, a reliable profitability assessment is not possible.
The seven final scores provide a clearer picture of run-line outcomes.
Date | Winning team | Winning margin | Seattle -1.5 result |
|---|---|---|---|
August 25 | Seattle | 2 | Won |
August 26 | Seattle | 1 | Lost |
August 27 | Cleveland | 1 | Lost |
August 28 | Seattle | 4 | Won |
September 2 | Seattle | 5 | Won |
September 3 | Seattle | 4 | Won |
September 4 | Seattle | 3 | Won |
Seattle would have covered a standard -1.5 run line in five of the seven games.
Cleveland +1.5 would have covered twice.
These outcomes do not establish profitability because the original run-line prices are unavailable.
The seven games produced the following combined run totals.
Date | Final score | Combined runs |
|---|---|---|
August 25 | 3-1 | 4 |
August 26 | 3-2 | 5 |
August 27 | 4-3 | 7 |
August 28 | 4-0 | 4 |
September 2 | 6-1 | 7 |
September 3 | 4-0 | 4 |
September 4 | 6-3 | 9 |
The teams combined for 40 runs across seven games, an average of approximately 5.7 per contest.
Five of the seven games finished with seven runs or fewer.
That reflects how effectively Seattle limited Cleveland's offense, particularly during the September series.
The original sportsbook totals are unavailable, so the number of winning Over or Under wagers cannot be established.
The original article is unavailable, and its exact game date has not been confirmed.
As a result, there is insufficient evidence to identify an official ATS.io selection.
Seattle's 6-1 season-series record does not establish which team, run line, or total the original author recommended.
Original ATS.io pick: Unverified
Original betting odds: Unverified
Confirmed 2022 head-to-head result: Seattle won 6-1
These distinctions are important when evaluating historical betting records.
A winning result should only be credited to a published selection when the original recommendation can be verified.
Both teams reached the postseason.
Cleveland won the AL Central with a 92-70 record.
The Guardians defeated Tampa Bay in the American League Wild Card Series before losing to the New York Yankees in five games in the Division Series.
Seattle finished 90-72 and secured a Wild Card berth.
The Mariners defeated Toronto in the Wild Card Series, ending a postseason drought that had lasted since 2001.
Their season ended with a three-game Division Series loss to the Houston Astros.
Both clubs exceeded many preseason expectations, although they followed different paths to October.
Cleveland's contact-oriented lineup and pitching depth helped it win a division title.
Seattle combined improved starting pitching with timely power hitting to reach the playoffs.
Seattle won six of the seven regular-season meetings.
They met seven times, with four games in Seattle and three in Cleveland.
Cleveland won 4-3 on August 27 at T-Mobile Park.
Seattle swept all three games at Progressive Field, winning 6-1, 4-0, and 6-3.
The September 4 game produced nine combined runs, with Seattle winning 6-3 in 11 innings.
Seattle shut out Cleveland twice, winning 4-0 on August 28 and September 3.
Seattle scored 29 runs, while Cleveland scored 11.
Yes. Cleveland won the AL Central, while Seattle qualified as a Wild Card team.
Cleveland finished 92-70, compared with Seattle's 90-72 record.
The Mariners acquired Luis Castillo from Cincinnati ahead of the trade deadline.
The original recommendation could not be recovered and remains unverified.
Visit ATS.io's MLB picks and predictions section for additional baseball coverage.
The Guardians and Mariners both reached the postseason in 2022, but their head-to-head meetings were heavily one-sided.
Seattle won six of seven games and held Cleveland to just 11 runs across the season series.
The Mariners' starting pitching was consistently effective, while their power hitters supplied important runs in several close contests.
Cleveland's only victory came through a late comeback on August 27.
The September rematch demonstrated Seattle's advantage even more clearly, with the Mariners completing a three-game road sweep.
→ Our Take: Seattle was the stronger team in this particular 2022 matchup, winning six of seven meetings and outscoring Cleveland 29-11. The Mariners' pitching depth and timely power hitting proved decisive. Those results are verified, but the original ATS.io prediction and betting odds remain unavailable, so no official winning pick can be credited.
For more historical matchups and current baseball analysis, visit our MLB betting coverage.