Ole Miss Rebels vs Oklahoma Sooners Prediction - November 15, 2026

Matchup Overview

Oklahoma enters with 22.11 points per game, 338.4 yards per game, and a balanced offense built around 227.6 passing yards and 110.9 rushing yards per game. Ole Miss has been the more productive offense at 33.78 points and 418.8 yards per game, led by 271.4 passing yards and 147.3 rushing yards per game, but the Rebels also allow 26.0 points and 394.67 yards per game. Oklahoma’s defense has been much tighter, giving up only 19.22 points and 293.33 yards per game, which creates a clear path for the Sooners to slow the game down and keep the scoring margin in their favor.

Market Trends

• ●Oklahoma Sooners are 4-5-0 against the spread and 3-6-0 to the over.
• ●Ole Miss Rebels are 4-5-0 against the spread and 6-3-0 to the over.

Prediction Summary

Oklahoma has the stronger defensive profile and the better side of the market price, making the Sooners the preferred position in a game that should stay competitive but tilt toward the home team. Ole Miss has the higher-powered offense, yet its defensive issues give Oklahoma enough room to control the game flow and make key stops. The projection calls for Oklahoma to win 27-24, which supports a narrow home cover and a total that lands in the low 50s.