Wednesday night’s non-conference game between the South Florida Bulls (3–1) and Oklahoma State Cowboys (4–0) will be an interesting one from Gallagher‑Iba Arena in Stillwater. Oklahoma State is undefeated on the season so far and they will try to get an impressive win over a USF team that has lit up the scoreboard eaerly in the season. Before tip-off from Stillwater, you can find my South Florida vs Oklahoma State prediction below.
Our South Florida vs Oklahoma State Pick
- Pick: Oklahoma State −5.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: South Florida Bulls @ Oklahoma State Cowboys
- Date & Time: Wednesday, November 19, 2025, 8:00 PM ET
- Venue: Gallagher‑Iba Arena, Stillwater, Oklahoma
- Broadcast: ESPN+
Key Storylines
OSU is coming off a dominant week, including a 94–67 victory over Prairie View A&M where Vyctorius Miller exploded for a career‑high 30 points on 8-of-12 shooting. Oklahoma State also has a win over Texas A&M under their belt this season and they have looked impressive early. The Cowboys bring a rebuilt roster under coach Steve Lutz and are showing early chemistry.
South Florida averages a blistering 101.3 points per game and ranks near the top nationally in free-throw makes per game. Their offense is powered by Josh Omojafo, who averages close to 20 points per game, and Joseph Pinion, who put up 24 in their recent win over Kennesaw State. The question for USF going into this game is whether or not they can pass their first real test of the season after beating up on lower-level competition like Florida A&M and Coppin State.
Another big storyline to monitor going into this game is the shooting efficiency for both sides. Both of these teams are shooting over 45% from the field early in the year. But they are facing a better defensive opponent in this game than they have faced in most of their early-season games. The team that can perform against a better defense here will have a great chance to collect another important win.
Head-to-Head & Betting Trends
- This is only the third meeting between these programs. Oklahoma State leads the all-time series 2–0, including a prior win in Stillwater.
- USF is 3-1 against the spread going into this game.
- Oklahoma State is 2-2 against the spread heading into Wednesday night.
- Oklahoma State has gone under the total in all four of their games for the year.
- The over has hit in three of their first four games of the season.
South Florida vs Oklahoma State Model Projection
Score Projection: South Florida 80 – Oklahoma State 88
Win Probability: South Florida 37%, Oklahoma State 63%
Final Thoughts
South Florida is a dangerous offensive team with scoring threats at multiple positions and they could make this a tight game if they catch fire. But Oklahoma State has the edge in pace, size, and balance. The Cowboys are also on their home floor, which should help them to get the win in this matchup. I’ll lay the points with Oklahoma State in what should be an entertaining matchup from Stillwater.
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