The Harvard Crimson and Boston University Terriers will face off Saturday in an interesting non-conference matchup in college basketball. Harvard is 4–2 and enters the Basketball Hall of Fame Showcase in Connecticut favored to continue their hot start. Boston University enters this game at 2–3 and sees this as an opportunity to pick up a quality win and shake off their inconsistent early-season start. Before tip-off from Mohegan Sun, continue reading to get my Harvard vs Boston University prediction.
Our Harvard vs Boston University Pick
- Pick: Harvard Crimson -3.5
- Confidence: ★★★☆☆
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Game Snapshot
- Matchup: Boston University Terriers vs Harvard Crimson
- Date & Time: Saturday, November 22, 2025, 1:30 PM ET
- Venue: Mohegan Sun Arena, Uncasville, Connecticut
- Broadcast: NESN
Key Storylines
- Harvard’s efficient offense: The Crimson are scoring at a solid clip, averaging 72.7 points per game while shooting 47.4% from the field and 39% from three-point range. Their guard play has been reliable, particularly from Chandler Pigge and Tey Barbour. Pigge averages 16.7 PPG, 4.5 assists, and 1.7 steals per game, while Barbour is contributing 11.5 PPG and 5.7 boards.
- BU’s three-point reliance: Boston University is averaging 8.2 made threes per game early in the season. Michael McNair stands out as a deep threat, hitting 46.9% from long range, with 3 made threes per game. He averages 13.8 PPG to lead the Terriers.
- Turnover battle: Harvard has coughed up 11.7 turnovers per game. The Crimson are 4–0 this season when they commit fewer turnovers than their opponent. They will have to take care of the basketball against the aggressive defense of BU in this contest.
- Injury and depth concerns for BU: In their most recent game, Boston University reportedly dressed only six players due to injuries and limited availability. That thin bench could be exploited if Harvard pushes tempo and applies enough pressure.
Betting Trends
- Harvard is 2-2 against the spread to start the season.
- Boston University is 3-2 against the spread going into this game.
- The Crimson have gone 2-2 in the over/under market as well.
- BU has gone over the total in three of its first five games.
Harvard vs Boston University Model Projection
Score Projection: Harvard 75 – Boston U 70
Win Probability: Harvard 62%, Boston U 38%
Final Thoughts
The lack of depth for Boston University right now is alarming. Even if they get some reinforcements back for this game, they are still going to be somewhat short-handed. That will cause problems against a team with the upside that Harvard possesses. I’ll lay the points with the Crimson here, as they should get the job done in this Boston-based rivalry game that is being played at a neutral site at Mohegan Sun Arena.
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