Creighton vs Seton Hall Pick: Prediction & Best Bet

Creighton and Seton Hall will collide in a key Big East conference contest on Sunday at Prudential Center in Newark. Both teams enter this meeting with winning records in Big East play and will try to keep trending in the right direction in this contest. Creighton is looking to extend a four-game winning streak and the Pirates are aiming to build on a nice road win over Marquette. Here, I break down all the action on the court and give you my Creighton vs Seton Hall prediction.

Our Creighton vs Seton Hall Pick

Pick:	Seton Hall -2.5
Confidence:	3/5

Game Snapshot

Matchup: Creighton Bluejays @ Seton Hall Pirates
Date & Time: January 4, 2026, 12:00 PM ET
Venue: Prudential Center, Newark, New Jersey
Broadcast: Peacock

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Key Storylines

Creighton enters this game on a four-game winning streak, including an 89-85 triumph over Butler in which Jasen Green poured in 23 points and dished out five assists. Creighton’s offense has been operating efficiently this season, with strong shooting numbers and balanced scoring across its rotation.
Seton Hall is 7-1 at home this season and looks to take advantage of that environment again in this contest. They most recently defeated Marquette 79-73, closing with a decisive 13-0 run after trailing by double digits earlier in the game. That kind of mental toughness is a huge part of Seton Hall's identity and will be a factor again in this contest.
Defensively, the Pirates are known for their physicality, and they are averaging 6.0 blocks per game as a team. This could challenge Creighton’s scoring inside if they fail to protect the ball well against a group that is good at blocking shots without fouling.
From a stylistic standpoint, this should be an interesting basketball game. Seton Hall likes to slow opponents down and let their defense do the work for them. But Creighton is capable of scoring at a more brisk tempo and it will be interesting to see if the Pirates can force Creighton to play the way they want to play basketball.

Head-to-Head & Betting Trends

These teams are 16-16 against each other all-time.
Creighton has won six straight games over Seton Hall.
Creighton is 6-8 against the spread this season.
Seton Hall is 9-5 against the spread going into this matchup.
The under has hit in 10 of the 14 games for Creighton this year.
The under is 8-6 in Seton Hall's games during the 2025-26 campaign.

Creighton vs Seton Hall Model Projection

Score Projection: Creighton 70 – Seton Hall 74

Win Probability: Creighton 47%, Seton Hall 53%

Final Thoughts

This should be a tightly contested Big East basketball game. I lean slightly toward the home team in this contest, as they should be able to impose their will defensively against a Creighton team that has gone 1-2 in true road games so far this season. Expect this one to come down to the wire, but for Seton Hall to win and cover the spread in the end.

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

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Key Storylines

Creighton enters this game on a four-game winning streak, including an 89-85 triumph over Butler in which Jasen Green poured in 23 points and dished out five assists. Creighton’s offense has been operating efficiently this season, with strong shooting numbers and balanced scoring across its rotation.

Seton Hall is 7-1 at home this season and looks to take advantage of that environment again in this contest. They most recently defeated Marquette 79-73, closing with a decisive 13-0 run after trailing by double digits earlier in the game. That kind of mental toughness is a huge part of Seton Hall's identity and will be a factor again in this contest.

Defensively, the Pirates are known for their physicality, and they are averaging 6.0 blocks per game as a team. This could challenge Creighton’s scoring inside if they fail to protect the ball well against a group that is good at blocking shots without fouling.

From a stylistic standpoint, this should be an interesting basketball game. Seton Hall likes to slow opponents down and let their defense do the work for them. But Creighton is capable of scoring at a more brisk tempo and it will be interesting to see if the Pirates can force Creighton to play the way they want to play basketball.

Head-to-Head & Betting Trends

These teams are 16-16 against each other all-time.

Creighton has won six straight games over Seton Hall.

Creighton is 6-8 against the spread this season.

Seton Hall is 9-5 against the spread going into this matchup.

The under has hit in 10 of the 14 games for Creighton this year.

The under is 8-6 in Seton Hall's games during the 2025-26 campaign.

Final Thoughts

Affiliate Disclosure

Creighton Bluejays vs Seton Hall Pirates Pick & Prediction - 1/4/2026

Our Creighton vs Seton Hall Pick

Game Snapshot

Key Storylines

Head-to-Head & Betting Trends

Creighton vs Seton Hall Model Projection

Final Thoughts

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Our Creighton vs Seton Hall Pick

Game Snapshot

Key Storylines

Head-to-Head & Betting Trends

Creighton vs Seton Hall Model Projection

Final Thoughts