Auburn Tigers vs Purdue Boilermakers Prediction & Picks - 12/20/2025
Updated December 20, 2025
Updated December 20, 2025
The Purdue Boilermakers and Auburn Tigers will square off on Saturday at Gainbridge Fieldhouse in Indianapolis. Both of these teams are ranked going into this matchup and will be looking to make a statement late in non-conference play. Here, I take a closer look at this matchup between teams from the SEC and Big Ten and give you my Auburn vs Purdue prediction for Saturday night.
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Score Projection: Purdue 81 – Auburn 71
Win Probability: Purdue 80%, Auburn 20%
I'm going to lay the points with Purdue in this matchup from Indianapolis. Purdue is better on the defensive end of the floor and that should translate to a pretty significant edge, especially when combined with the crowd in Indy likely to be pro-Purdue. Look for the Boilermakers to win this contest by double-digits and to move themselves closer to a return to the top 5 in the rankings.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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