Albany Great Danes vs Siena Saints Prediction - 11/21/2025

The UAlbany Great Danes will look to defend their Albany Cup crown in a Friday night game against the Siena Saints. This crosstown rivalry will be reignited at MVP Arena in Albany, where UAlbany hopes to get its first win over a Division I opponent this season at the expense of a Siena team that has dropped two straight. I've covered both of these programs and cannot wait to see this game unfold. Continue reading to get my UAlbany vs Siena prediction for Friday night.

Our UAlbany vs Siena Pick

• Pick: UAlbany +10.5
• Confidence: 3/5

Game Snapshot

• Matchup: UAlbany Great Danes @ Siena Saints
• Date & Time: November 21, 2025, 7:00 PM ET
• Venue: MVP Arena, Albany, New York
• Broadcast: ESPN+

Key Storylines

• Albany’s early issues: The Great Danes are off to a 2–3 start but both of their wins have come against schools from below the Division I level. Even scheduling SUNY Delhi and Paul Smith's (which is a great place to go on a nature walk, I can confirm) is embarrassing for a Division I program to do. The Danes have lost all three of their games against Division I opponents by double-digits and will try to end that streak here.
• Balanced attack: UAlbany is not relying on just one scorer. Five players average double figures through five games. Amir Lindsey leads the team with 16.3 points per game, but they have multiple players who can score and put pressure on Siena's defense.
• Siena’s bounce-back opportunity: The Saints are 2–2 so far this season. They won their first two games of the year against Bryant and Brown before losing consecutive games to St. Bonaventure and Colgate. Their top scorer is Gavin Doty at 17.3 points per game, who is connecting at 49.1% from the field. He will attempt to lead Gerry McNamara's team to a win in this Albany-area rivalry game.
• Albany Cup renewal: This is the first game under the new four-year home-and-home Albany Cup contract between the schools. The rivalry is one of the most anticipated sporting events in Albany, NY every year, especially now that Antonio Brown has moved on from owning the local arena football team to becoming a murder suspect (allegedly, please don't sue me, Antonio Brown).

Head-to-Head & Betting Trends

The rivalry between UAlbany and Siena stretches back decades, though in recent years Albany has had more success. Over the past 10 meetings, UAlbany holds a 7–3 edge. Historically, Siena leads the overall series, but the Great Danes have been dominant in this more recent stretch.

UAlbany is 0-3 against the spread in their three games against Division I opponents this year. They have gone under the total in all three of those games. Siena is 3-1 against the spread this season and has stayed under the total in three of their four outings thus far.

UAlbany vs Siena Model Projection

Score Projection: UAlbany 69 – Siena 77

Win Probability: Siena 65%, UAlbany 35%

Final Thoughts

College basketball is better when this rivalry game takes place, even if both teams have redesigned their mascots to look like they have been diagnosed with depression. The Great Danes have performed well in this game in recent years. But UAlbany has looked horrible against Division I competition so far this year. I think Siena wins this game, but the Great Danes cover the spread as they rise to the challenge and keep this one competitive with the Albany Cup on the line.

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