The Portland Trail Blazers (7–9) head to Milwaukee on Monday night to face the Bucks (8–9) in a crucial opportunity for both teams. Milwaukee is trying to halt a four‑game losing streak, while Portland is seeking a confidence-boosting road win despite being depleted by injuries. This game is close to a pick ’em and you can continue reading to get my Trail Blazers vs Bucks prediction for Monday’s inter-conference matchup.
Our Trail Blazers vs Bucks Pick
Pick: Trail Blazers Moneyline
Confidence: ★★☆☆☆
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Game Snapshot
- Matchup: Portland Trail Blazers @ Milwaukee Bucks
- Date & Time: Monday, November 24, 2025, 8:00 PM ET
- Venue: Fiserv Forum, Milwaukee, WI
- Broadcast: NBA League Pass
Key Storylines
- Injury crisis in Portland: The Blazers are missing a huge chunk of their roster. Scoot Henderson (hamstring), Jrue Holiday (calf), Shaedon Sharpe (calf), Robert Williams III (knee), Matisse Thybulle (thumb), and Blake Wesley (foot) are all unavailable or questionable. Damian Lillard is out for the season as well.
- Giannis out in Milwaukee: The Bucks will be without Giannis Antetokounmpo (groin), which is a major blow to their frontcourt and overall offensive firepower.
- Blazers leaning on Avdija: Deni Avdija has emerged as Portland’s go‑to guy, averaging 25.1 points per game. With so many players out for Portland, Avdija needs to continue to step up to help Portland remain competitive.
- Bucks’ role players must step up: With Giannis out, the onus is on Kyle Kuzma, Myles Turner, Ryan Rollins, and others to carry the offensive load.
- Milwaukee’s skid: The Bucks are entering this game on a four-game losing streak and are under pressure to regroup at home. Portland has dropped four of its last five games and will try to bounce back as well.
Head-to-Head & Betting Trends
- ATS Trends: Portland is 8–9–0 against the spread this season. Milwaukee is 7-10 against the spread going into this contest.
- Over/Under Trends: The Trail Blazers have gone over the total in 12 of their first 17 games. Milwaukee is 10-7 to the over on the year.
- Home/Road Splits: Milwaukee has gone 5–5 at home so far this season. Portland is 4–6 on the road.
- Head-to-Head: This is the first meeting between these teams this season.
Best Player Props to Watch
| Player | Prop |
|---|---|
| Deni Avdija (POR) | Over 24.5 Points |
| Ryan Rollins (MIL) | Under 23.5 Points |
| Myles Turner (MIL) | Over 1.5 Blocks |
Trail Blazers vs Bucks Model Projection
Score Projection: Trail Blazers 125 – Bucks 123
Win Probability: Blazers 55%, Bucks 45%
Final Thoughts
I’m expecting the Trail Blazers to bounce back nicely in this game after getting blown out by Oklahoma City on Sunday. Expect Portland to take advantage of the absence of Antetkounmpo, which will allow the Trail Blazers to focus more on defending the three-point line. I’ll take the Trail Blazers to win as a slight underdog at Fiserv Forum behind another big game from Deni Avdija.

